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Quality of life before and one year following stem cell transplantation using an individualized and a standardized instrument
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences.
2008 (English)In: Psycho-Oncology, ISSN 1057-9249, E-ISSN 1099-1611, Vol. 17, no 4, 338-346 p.Article in journal (Refereed) Published
Abstract [en]

Objective: The aim was to prospectively measure quality of fife in patients with malignant blood disorders following stem cell transplantation (SCT) using an individualized and a standardized measure. Methods: Twenty-two consecutive patients were assessed before and one year following SCT, using a generic and disease-related version of the Schedule for the Evaluation of Individual Quality of Life-Direct Weighting (SEIQoL-DW) and the EORTC QLQ-C30. Results of the QLQ-C30 were compared with Swedish norm values. Results: A majority of the patients reported concerns related to health before as well as one year after SCT, recorded by both instruments. Mean scores produced by the SEIQoL-DW, and four scales of the EORTC QLQ-C30, showed a change over time, indicating improved quality of life one year after SCT. In comparison with Swedish norm values for the EORTC QLQ-C30, SCT recipients reported a worse functioning. Conclusions: In addition to well-known disease and treatment-related problems, areas not typically included in standardized instruments were nominated in the disease-related SEIQoL-DW. Such areas included positive aspects, e.g. a changed view of fife and oneself. The results support the use of the generic and disease-related SEIQoL-DW to achieve a comprehensive picture of patient's clinical situation under treatment or when recovering from illness.

Place, publisher, year, edition, pages
2008. Vol. 17, no 4, 338-346 p.
Keyword [en]
cancer, EORTC, health-related quatity of life, oncollogy, SEIQoL-DW, stem cell transplantation
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-110221DOI: 10.1002/pon.1240ISI: 000255372400003PubMedID: 17614094OAI: oai:DiVA.org:uu-110221DiVA: diva2:275596
Available from: 2009-11-06 Created: 2009-11-05 Last updated: 2017-12-12Bibliographically approved

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