Detecting Virus-like Particles Using Transmission Electron Microscopy
2009 (English)In: Proceedings SSBA 2009, Symposium on Image Analysis / [ed] Josef Bigun, Antanas Verikas, Halmstad: EIS, Halmstad University , 2009, 13-16 p.Conference paper (Other academic)
We present a multi scale approach for automating the image acquisition process for an computerized virus diagnostic application. Our methods are designed to mimic the methodology used by virus TEM experts manually operating the microscope. The methods decrease the search area considerably. In addition we present a segmentation method for virus-like particles based on local intensity information and PCA. This method makes no assumption regarding shape which is vital since many viruses are highly pleomorphic, i.e., have different shapes. The only input parameter used is the approximate virus thickness, which is a conserved feature within a virus species.
Place, publisher, year, edition, pages
Halmstad: EIS, Halmstad University , 2009. 13-16 p.
Computer Vision and Robotics (Autonomous Systems)
Research subject Computerized Image Analysis
IdentifiersURN: urn:nbn:se:uu:diva-111459ISBN: 978-91-633-3924-0OAI: oai:DiVA.org:uu-111459DiVA: diva2:281283
Symposium on Image Analysis