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Insect hemolymph clotting
Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Physiology and Developmental Biology, Comparative Physiology.
2009 (English)In: Cellular and Molecular Life Sciences (CMLS), ISSN 1420-682X, E-ISSN 1420-9071, Vol. 66, no 16, 2643-2650 p.Article, review/survey (Refereed) Published
Abstract [en]

The clot's appearance in different large-bodied insects has been described, but until recently, little was known about any insect clot's molecular makeup, and few experiments could directly test its function. Techniques have been developed in Drosophila (fruit fly) larvae to identify clotting factors that can then be tested for effects on hemostasis, healing, and immunity. This has revealed unanticipated complexity in the hemostatic mechanisms in these larvae. While the clot's molecular structure is not yet fully understood, progress is being made, and the loss of clotting factors has been shown to cause subtle immune defects. The few similarities between coagulation in different insect species and life stages, and the current state of knowledge about coagulation in insects are discussed.

Place, publisher, year, edition, pages
2009. Vol. 66, no 16, 2643-2650 p.
Keyword [en]
Clotting, insect, immune system
National Category
Biological Sciences
Research subject
Biology with specialization in Comparative Physiology
URN: urn:nbn:se:uu:diva-114231DOI: 10.1007/s00018-009-0036-0ISI: 000268295100003PubMedID: 19418022OAI: oai:DiVA.org:uu-114231DiVA: diva2:293562
Available from: 2010-02-12 Created: 2010-02-12 Last updated: 2011-01-19Bibliographically approved

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