uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
Morphological studies on machined implants of commercially pure titanium and titanium alloy (Ti6Al4V) in the rabbit
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Applied Materials Sciences.
Show others and affiliations
2009 (English)In: Journal of biomedical materials research. Part B, ISSN 1552-4973, Vol. 91B, no 1, 309-319 p.Article in journal (Refereed) Published
Abstract [en]

The aim of this study was to evaluate the bone response to commercially   pure titanium grade I and titanium alloy grade V (90% Ti, 6% Al, and 4%   V, depicted Ti6Al4V) after 8 weeks in rabbit tibia. Interference   microscopy and scanning electron microscopy were used for surface   analyses. Transmission electron microscopy (TEM) was used for   evaluation of surface crystallinity and chemistry after preparation of   ultrathin sections using focused ion beam (FIB) microscopy. Three   different embedding resins commonly used for histological preparation   were evaluated with respect to adaptation to a turned implant surface.   Epoxy Agar 100 resin and acrylic Technovit 7200 resin showed low   separation while acrylic LR White resin showed large separation at the   interface. The retrieved specimens were embedded in acrylic Technovit   7200 resin after fixation and dehydration. The histological evaluation   revealed osseointegration for both c.p. titanium grade I and Ti6Al4V   alloy, but no quantitative differences in bone contact and bone area   were detected. Because a separation of implant and tissue occurred in   the interface between implant and bone embedded in acrylic Technovit   7200 resin, additional factors related to implant surface properties   and technical procedures are likely to influence the possibilities to   prepare ultrathin sections by FIB.

Place, publisher, year, edition, pages
2009. Vol. 91B, no 1, 309-319 p.
Keyword [en]
titanium, titanium alloy, histology, FIB, embedding resins, osseointegration
National Category
Engineering and Technology
URN: urn:nbn:se:uu:diva-117595DOI: 10.1002/jbm.b.31404ISI: 000269897100035OAI: oai:DiVA.org:uu-117595DiVA: diva2:298083
Available from: 2010-02-21 Created: 2010-02-21 Last updated: 2016-04-14Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text

Search in DiVA

By author/editor
Engqvist, Håkan
By organisation
Applied Materials Sciences
Engineering and Technology

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 346 hits
ReferencesLink to record
Permanent link

Direct link