Chemical shift artifact-free microscopy: spectroscopic microimaging of the human skin.
1999 (English)In: Magnetic Resonance in Medicine, ISSN 0740-3194, Vol. 41, no 5, 904-8 p.Article in journal (Refereed) Published
A spectroscopic imaging technique with high spatial resolution was used for the study of human skin in vivo. The measurements were performed using a whole-body magnetic resonance system (1.5 T) with standard gradients and a standard 8-cm diameter circular surface coil. A decisive gain in signal-to-noise ratio was achieved by reducing the receiver bandwidth of the imaging system to values less than +/-5 kHz. The chemical shift misregistration was eliminated by post-detection data processing. The method was tested on different kinds of skin, on the foot sole and head. Water, fat, and chemical shift artifact-free images were obtained with resolution 0.107 x 0.143 mm in plane and slice thickness 1 mm. A major advantage of the spectroscopic imaging procedure is that the pulse sequence can be optimized for the maximum signal-to-noise ratio. There is no need for special modification of the sequence to circumvent the chemical shift artifacts (water, fat suppression, etc.).
Place, publisher, year, edition, pages
1999. Vol. 41, no 5, 904-8 p.
magnetic resonnace spectroscopy, micro-imaging
Medical and Health Sciences
Research subject Radiology
IdentifiersURN: urn:nbn:se:uu:diva-109808PubMedID: 10332872OAI: oai:DiVA.org:uu-109808DiVA: diva2:300446