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Genetically modified plants for non-food or non-feed purposes: straightforward screening for their appearance in food and feed
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Genetics and Pathology.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
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2010 (English)In: Food and Chemical Toxicology, ISSN 0278-6915, E-ISSN 1873-6351, Vol. 48, no 2, 453-464 p.Article in journal (Refereed) Published
Abstract [en]

Genetically modified (GM) plants aimed at producing food/feed are part of regular agriculture in many areas of the World. Commodity plants have also found application as bioreactors, designated non-food/non-feed GM (NFGM) plants, thereby making raw material for further refinement to industrial, diagnostic or pharmaceutical preparations. Many among them may pose health challenge to consumers or livestock animals, if occurring in food/feed. NFGM plants are typically released into the environment, but are grown under special oversight and any among several containment practices, none of which provide full protection against accidental dispersal. Adventitious admixture with food or feed can occur either through distributional mismanagement or as a consequence of gene flow to plant relatives. To facilitate NFGM surveillance we propose a new mandatory tagging of essentially all such plants, prior to cultivation or marketing in the European Union. The suggested tag--Plant-Made Industrial or Pharmaceutical Products Tag (PMIP-T)--is envisaged to occur as a transgenic silent DNA identifier in host plants and designed to enable technically simple identification and characterisation of any NFGM. Implementation of PMIP-T would permit inexpensive, reliable and high-throughput screening for NFGM specifically. The paper outlines key NFGM prospects and challenges as well as the PMIP-T concept.

Place, publisher, year, edition, pages
2010. Vol. 48, no 2, 453-464 p.
National Category
Biochemistry and Molecular Biology
URN: urn:nbn:se:uu:diva-119772DOI: 10.1016/j.fct.2009.10.049ISI: 000275007700001PubMedID: 20004226OAI: oai:DiVA.org:uu-119772DiVA: diva2:300891
Available from: 2010-03-01 Created: 2010-03-01 Last updated: 2011-02-24Bibliographically approved

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Alderborn, Anders
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Department of Genetics and PathologyDepartment of Medical Sciences
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