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PHASE-20: Ett nytt instrument för skattning av möjliga läkemedelsrelaterade symtom hos äldre personer i äldreboende
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences.ORCID iD: 0000-0001-6296-0160
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience, Medicinal history.
2009 (Swedish)In: Vård i Norden, ISSN 0107-4083, E-ISSN 1890-4238, Vol. 29, no 4, 9-14 p.Article in journal (Refereed) Published
Abstract [en]


Elderly persons may easily develop adverse drug effects. In Sweden, at least seven untested instruments are used for assessing possible drug-related symptoms in elderly people.


The aim was to develop a more valid and reliable instrument for identification of possible therapeutic drug-related symptoms.


The seven pre-existing instruments consisted of 39 symptoms, which were coordinated and then analyzed for content validity.  After revision, the instrument included 19 symptoms or symptom-groups and one open variable. To assess the construct validity and reliability, the new instrument, PHASE-20, was tested in a randomized controlled trial with elderly persons living in two nursing homes before and after evaluation and correction of their therapeutic drugs.


PHASE-20 was found to possess an acceptable consistency, test-retest reliability, and internal validity. Construct validity was not supported in this study, as there were no significant differences between groups after the intervention. Therapeutic drug-related symptoms among elderly might be too heterogeneous to be captured into a screening instrument. However, PHASE-20 was welcomed by both patients and staff as a well structured, easily understandable, and useful assessment instrument.


PHASE-20 can be used for identifying possible drug-related symptoms among elderly who are able to cooperate at least partly.

Place, publisher, year, edition, pages
2009. Vol. 29, no 4, 9-14 p.
Keyword [en]
aged, drug utilization, geriatric nursing, nursing assessment
National Category
Nursing Pharmaceutical Sciences
URN: urn:nbn:se:uu:diva-120054OAI: oai:DiVA.org:uu-120054DiVA: diva2:302375
Available from: 2010-03-05 Created: 2010-03-05 Last updated: 2016-09-25

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Hedström, MariannHulter Åsberg, Kerstin
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