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Personalized medicine in psychiatry: ethical challenges and opportunities
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Centre for Research Ethics and Bioethics. (CRB)
2009 (English)In: Dialogues in Clinical Neuroscience, Vol. 11, no 4, 427-433 p.Article in journal (Refereed) Published
Abstract [en]

Pharmacogenomic developments hold out promises of personalized medicine in psychiatry with adjusted therapeutic doses, predictable responses, reduced adverse drug reactions, early diagnosis, and personal health planning. The prospects are exciting, but at the same time, these new techniques stand faced with important scientific, ethical, legal and social challenges that need to be met in order for the scientific advances to be responsibly applied. This review discusses the ethical balance between challenge and opportunity of personalized medicine in psychiatry under the aspects of adequacy, cost-benefit ratio, and therapeutic equity. It is argued that the promising nature of these therapeutic possibilities make it all the more important to avoid exaggerating the expectations, and that a sophisticated social infrastructure needs to be developed in order to ensure the realistic and responsible application of personalized medicine in psychiatry.

Place, publisher, year, edition, pages
2009. Vol. 11, no 4, 427-433 p.
Keyword [en]
psychopharmacology, pharmacogenomics, personalized medicine, promotion versus hype, cost-benefit ratio, therapeutic equity
National Category
Pharmacology and Toxicology
Research subject
Biopharmaceutics
Identifiers
URN: urn:nbn:se:uu:diva-122329PubMedID: 20135900OAI: oai:DiVA.org:uu-122329DiVA: diva2:309726
Available from: 2010-04-08 Created: 2010-04-08 Last updated: 2010-11-30Bibliographically approved

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