Metalworking exposures and persistent skin symptoms in the ECRHS II and SAPALDIA 2 cohorts
2009 (English)In: Contact Dermatitis, ISSN 0105-1873, E-ISSN 1600-0536, Vol. 60, no 5, 256-263 p.Article in journal (Refereed) Published
BACKGROUND: Diseases of the skin are important and often preventable conditions occurring among workers with dermal exposures to irritant and sensitizing agents. OBJECTIVE: We conducted this analysis to assess the associations between metalworking exposures and current and persistent skin symptoms among male and female participants in two population-based epidemiologic studies. METHODS: We pooled data from the European Community Respiratory Health Survey II (ECRHS II) and the Swiss Cohort Study on Air Pollution and Lung and Heart Disease in Adults 2 (SAPALDIA 2), two prospective cohort studies in Europe. Each participant completed interviewer-administered questionnaires to provide information about symptoms and exposures related to selected occupations, including metalworking, during the follow-up periods. We assessed associations between skin symptoms and the frequency of metalworking exposures among 676 ECRHS II/SAPALDIA 2 respondents. RESULTS: Current skin symptoms were reported by 10% of metalworkers and were associated with frequent use, defined as four or more days per week, of oil-based metalworking fluids [prevalence ratio (PR): 1.76, 95% confidence interval (CI): 1.25-2.49)] and organic solvent/degreasing agents (PR: 2.06, 95% CI: 1.21-3.50). CONCLUSIONS: Skin symptom prevalence is associated with increasing frequency of oil-based metalworking fluid and degreasing agent use. Our findings justify assessing strategies for reducing the frequency of metal-related exposures.
Place, publisher, year, edition, pages
2009. Vol. 60, no 5, 256-263 p.
contact dermatitis, epidemiology, metals, occupational diseases, occupational exposure
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:uu:diva-122944DOI: 10.1111/j.1600-0536.2009.01525.xISI: 000265481000002PubMedID: 19397617OAI: oai:DiVA.org:uu-122944DiVA: diva2:311451