uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
Domestic use of hypochlorite bleach, atopic sensitization, and respiratory symptoms in adults
Show others and affiliations
2009 (English)In: Journal of Allergy and Clinical Immunology, ISSN 0091-6749, E-ISSN 1097-6825, Vol. 124, no 4, 731-738 p.Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Professional use of hypochlorite (bleach) has been associated with respiratory symptoms. Bleach is capable of inactivating allergens, and there are indications that its domestic use may reduce the risk of allergies in children. OBJECTIVE: To study the associations between household use of bleach and atopic sensitization, allergic diseases, and respiratory health status in adults. METHODS: We identified 3626 participants of the European Community Respiratory Health Survey II in 10 countries who did the cleaning in their homes and for whom data on specific serum IgE to 4 environmental allergens were available. Frequency of bleach use and information on respiratory symptoms were obtained in face-to-face interviews. House dust mite and cat allergens in mattress dust were measured in a subsample. Associations between the frequency of bleach use and health outcomes were evaluated by using multivariable mixed logistic regression analyses. RESULTS: The use of bleach was associated with less atopic sensitization (odds ratio [OR], 0.75; 95% CI, 0.63-0.89). This association was apparent for specific IgE to both indoor (cat) and outdoor (grass) allergens, and was consistent in various subgroups, including those without any history of respiratory problems (OR, 0.85). Dose-response relationships (P < .05) were apparent for the frequency of bleach use and sensitization rates. Lower respiratory tract symptoms, but not allergic symptoms, were more prevalent among those using bleach 4 or more days per week (OR, 1.24-1.49). The use of bleach was not associated with indoor allergen concentrations. CONCLUSION: People who clean their homes with hypochlorite bleach are less likely to be atopic but more likely to have respiratory symptoms.

Place, publisher, year, edition, pages
2009. Vol. 124, no 4, 731-738 p.
Keyword [en]
Hypochlorite bleach, household, atopy, allergy, respiratory
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-122950DOI: 10.1016/j.jaci.2009.06.007ISI: 000270802800017PubMedID: 19665775OAI: oai:DiVA.org:uu-122950DiVA: diva2:311474
Available from: 2010-04-21 Created: 2010-04-21 Last updated: 2010-07-01Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed
By organisation
Occupational and Environmental Medicine
In the same journal
Journal of Allergy and Clinical Immunology
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 178 hits
ReferencesLink to record
Permanent link

Direct link