uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
Use of snus and risk for cardiovascular disease: results from the Swedish Twin Registry
Show others and affiliations
2009 (English)In: Journal of Internal Medicine, ISSN 0954-6820, E-ISSN 1365-2796, Vol. 265, no 6, 717-724 p.Article in journal (Refereed) Published
Abstract [en]


To study the association between snus use and the risk for cardiovascular disease, i.e. ischemic heart disease and stroke.



Cohort study.






Sixteen thousand six hundred and forty-two male Swedish twins participating in the Screening Across the Lifespan Twin Study, conducted in 1998- 2002, were followed for incident cardiovascular disease. Participants were without a history of cardiovascular disease at baseline and incident cases were identified via the Swedish Cause of Death Register and Hospital Discharge Register.


Overall, there was no association between use of snus and risk for cardiovascular disease. Current snus users, without a smoking history, had a relative risk of 1.00 (95% confidence interval 0.69-1.46) for cardiovascular disease as compared to non users. Corresponding relative risks for ischemic heart disease and stroke were 0.85 (95% confidence interval 0.51-1.41) and 1.18 (95% confidence interval 0.67-2.08), respectively. In smoking adjusted models, risk estimates for ischemic heart disease in relation to snus use were all close to unity regardless of timing or intensity of snus use. However, current heavy snus users (consuming more than four cans week(-1)) had a relative risk for stroke of 1.75 (95% confidence interval 0.95-3.21).



These data do not support any strong association between snus use and risk for cardiovascular disease.

Place, publisher, year, edition, pages
2009. Vol. 265, no 6, 717-724 p.
Keyword [en]
cardiovascular disease, ischemic heart disease, smokeless tobacco, snus, stroke
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-123670DOI: 10.1111/j.1365-2796.2009.02081.xISI: 000265894000011PubMedID: 19504754OAI: oai:DiVA.org:uu-123670DiVA: diva2:315253
Available from: 2010-04-28 Created: 2010-04-28 Last updated: 2012-07-25Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Hallqvist, Johan
By organisation
Family Medicine and Preventive Medicine
In the same journal
Journal of Internal Medicine
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 167 hits
ReferencesLink to record
Permanent link

Direct link