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Ulysses contracts for the doctor and for the patient
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Centre for Research Ethics and Bioethics.
2010 (English)In: Contemporary Clinical Trials, ISSN 1559-2030, Vol. 31, no 3, 202-206 p.Article in journal (Refereed) Published
Abstract [en]

Research subjects participating in randomised clinical trials have a right to drop out of a study without specifying any reason for this. However, leaving a trial may be contradictory to their own general interests in medical research since drop outs may lead to biased conclusions and loss of valuable medical information. We suggest in this paper that self-binding "Ulysses contracts" that are non-exploitative and based on autonomous decisions by research subjects as well as by investigating doctors should be implemented with stopping rules adjusted to the needs of different kinds of randomised clinical trials.

Place, publisher, year, edition, pages
2010. Vol. 31, no 3, 202-206 p.
Keyword [en]
Ethics, Autonomy, Informed consent, Withdrawal of consent
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-124712DOI: 10.1016/j.cct.2010.03.004ISI: 000277811300002PubMedID: 20227524OAI: oai:DiVA.org:uu-124712DiVA: diva2:317905
Available from: 2010-05-05 Created: 2010-05-05 Last updated: 2010-12-13Bibliographically approved

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Hansson, Mats G
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