Photochemical effects in the lens from near infrared radiation?
2009 (English)In: Proceedings of SPIE, the International Society for Optical Engineering, ISSN 0277-786X, Vol. 7163, 716311- p.Article in journal (Refereed) Published
Conclusion: The current data are consistent with a potential photochemical effect of in vivo exposure of the crystalline lens to near infrared radiation since the onset of cataract after in just above threshold dose was at least 18 hrs delayed after the exposure. Materials and methods: The eyes of 6 weeks old Sprague-Dawley rats were exposed unilaterally in vivo to 1090 nm, 6.2 W quasi-top hat spatial distribution with a 3 mm spot on the anterior lens surface within the dilated pupil. First, four exposure time groups of rats were exposed to increasing exposure times. At 24 hrs after exposure, the difference of light scattering between the lenses from the same animal was measured. Then, based on the first experiment, four post-exposure time groups were exposed unilaterally in vivo to 8 s of 1090 nm, 6.2 W quasi-top hat spatial distribution with a 3 mm spot on the anterior lens surface within the dilated pupil. After, the intended post-exposure time, the difference of light scattering between the lenses from the same animal was measured. Results: A 3 mm spot of 6.2 W induces light scattering in the lens with exposures of at least 8 s. Further, after 8 s of 6.2 W within a 3 mm spot on the lens surface, the light scattering increase in the lens was delayed at least 18 hrs after the exposure.
Place, publisher, year, edition, pages
San José, CA: SPIE , 2009. Vol. 7163, 716311- p.
infrared radiation, cataract, photochemical
Medical and Health Sciences
Research subject Ophtalmology
IdentifiersURN: urn:nbn:se:uu:diva-125006DOI: 10.1117/12.816848ISI: 000284821000022ISBN: 9780819474094OAI: oai:DiVA.org:uu-125006DiVA: diva2:318241