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Determinants for a low health-related quality of life in asthmatics
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Occupational and Environmental Medicine.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Occupational and Environmental Medicine.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Respiratory Medicine and Allergology.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Family Medicine and Clinical Epidemiology.
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2012 (English)In: Upsala Journal of Medical Sciences, ISSN 0300-9734, E-ISSN 2000-1967, Vol. 117, no 1, 57-66 p.Article in journal (Refereed) Published
Abstract [en]

People with asthma suffer from impaired health-related quality of life (HRQL) but the determinants of HRQL among asthmatics are not completely understood. The aim of this study was to study determinants of low HRQL in asthmatics and to study whether the determinants of HRQL differ between sexes and age groups.

A cohort of three age groups in Sweden was investigated in 1990 using a respiratory questionnaire. To study quality of life, the generic instrument Gothenburg Quality of Life was used. The participants were also investigated with interviews, spirometry and allergy testing. Asthma was diagnosed in 616 subjects.

Fifty-eight percent (n=359) of the subjects were women. Twenty-four percent were smokers, 22% ex-smokers and 54% were non-smokers. Women were more likely than men to report poor health-related quality of life. Respiratory symptoms severity was another independent determinant of a lower quality of life as well as airway responsiveness to irritants. Current and former smokers also reported lower quality of life. Finally, absenteeism from school and work was associated with lower quality of life.

Factors such as sex, smoking habits, airway responsiveness to irritants, respiratory symptom severity, allergy, and absenteeism from school and work were associated with low HRQL in asthmatics.

Place, publisher, year, edition, pages
2012. Vol. 117, no 1, 57-66 p.
Keyword [en]
asthma, GQL, quality of life, generic instrument, prognostic
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Research subject
Occupational and Environmental Medicine
Identifiers
URN: urn:nbn:se:uu:diva-129457DOI: 10.3109/03009734.2011.638730ISI: 000300304000010OAI: oai:DiVA.org:uu-129457DiVA: diva2:343883
Available from: 2010-08-16 Created: 2010-08-16 Last updated: 2017-12-12Bibliographically approved

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Leander, MaiLampa, ErikJanson, ChristerSvärdsudd, KurtUddenfeldt, MonicaRask-Andersen, Anna

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Occupational and Environmental MedicineRespiratory Medicine and AllergologyFamily Medicine and Clinical Epidemiology
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Public Health, Global Health, Social Medicine and Epidemiology

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