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A cessation program for snuff-dippers with long-term, extensive exposure to Swedish moist snuff: A 1-year follow-up study
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Oral and Maxillofacial Surgery.
2010 (English)In: Acta Odontologica Scandinavica, ISSN 0001-6357, Vol. 68, no 6, 377-384 p.Article in journal (Refereed) Published
Abstract [en]

Objective: Smokeless tobacco (Swedish moist 'snus') users are often strongly addicted to nicotine. Compared to the large number of smoking-cessation studies, there have been few evaluated clinical cessation programs in conjunction with nicotine replacement therapy (NRT). The aim of this study was to evaluate a cessation program for snus users with a weekly use of >2 cans/week for >10 years. Material and methods: A prospective, open, non-randomized intervention trial was undertaken including baseline oral examination and soft tissue biopsy, minor physical examination, brief cessation advice, NRT recommendations and five prospective follow-up visits within 12 months. Individual cessation counseling was given, together with oral examination in the dental office. Fifty snus users with a minimum consumption of 100 g/week who were actively seeking cessation treatment were recruited through advertising. Self-reported abstaining, including random-sample biochemical verification, and NRT use were evaluated at 6 weeks and 3, 6 and 12 months. Results: At the 3-, 6- and 12-month visits, 58%, 46% and 30% of subjects, respectively were tobacco-abstinent. All nicotine abstinence was randomly controlled during the study except at 12 months, where all subjects claiming abstinence were confirmed biochemically and clinically. Conclusion: Smokeless tobacco cessation achieved together with suitable NRT seems a promising way to improve a persistent tobacco-free condition.

Place, publisher, year, edition, pages
2010. Vol. 68, no 6, 377-384 p.
Keyword [en]
Cessation, nicotine replacement, oral mucosa, smokeless tobacco, snus
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-131012DOI: 10.3109/00016357.2010.514734ISI: 000282895600009PubMedID: 20831357OAI: oai:DiVA.org:uu-131012DiVA: diva2:352419
Available from: 2010-09-21 Created: 2010-09-21 Last updated: 2013-08-15Bibliographically approved

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Hirsch, Jan M.
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