Apolipoprotein B/A-I ratio related to visceral but not to subcutaneous adipose tissue in elderly Swedes
2010 (English)In: Atherosclerosis, ISSN 0021-9150, E-ISSN 1879-1484, Vol. 211, no 2, 656-659 p.Article in journal (Refereed) Published
OBJECTIVE: To investigate whether the amount of visceral (VAT) or subcutaneous adipose tissue (SAT) independently of the other can determine the apolipoprotein (apo)B/A-I ratio. METHODS: VAT and SAT areas were assessed using magnetic resonance imaging in 247 randomly selected 70-year-old men and women who did not use lipid-lowering drugs. Their adipose tissue areas were compared to their apoB and apo A-I levels and to their apoB/A-I ratios. RESULTS: The VAT area and the gender were significantly related to the apoB/A-I ratio whereas the SAT area was not. There was a positive relationship between the VAT area and the apoB/A-I ratio. CONCLUSION: A positive relationship was established between the amount of VAT and the apoB/A-I ratio, whereas there was no relationship between the amount of SAT and the apoB/A-I ratio. This observation supports the notion that VAT is metabolically active.
Place, publisher, year, edition, pages
2010. Vol. 211, no 2, 656-659 p.
ApoB/A-I ratio, Visceral adipose tissue, Subcutaneous adipose tissue, Apolipoprotein, Magnetic resonance imaging
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:uu:diva-132547DOI: 10.1016/j.atherosclerosis.2010.03.022ISI: 000280612700052PubMedID: 20382384OAI: oai:DiVA.org:uu-132547DiVA: diva2:358274