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Oxytocin as feeding inhibitor: maintaining homeostasis in consummatory behavior
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience. (Functional Pharmacology/Funktionell Farmakologi)
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience. (Functional Pharmacology/Funktionell Farmakologi)
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience. (Functional Pharmacology/Funktionell Farmakologi)
2010 (English)In: Pharmacology, Biochemistry and Behavior, ISSN 0091-3057, E-ISSN 1873-5177, Vol. 97, no 1, 47-54 p.Article, review/survey (Refereed) Published
Abstract [en]

Initial studies showed that the anorexigenic peptide oxytocin (OT) regulates gastric motility, responds to stomach distention and to elevated osmolality, and blocks consumption of toxic foods. Most recently, it has been proposed to act as a mediator of general and carbohydrate-specific satiety and regulator of body weight. In the current review, we discuss the function of OT as a homeostatic inhibitor of consumption, capable of mitigating multiple aspects of ingestive behavior and energy metabolism.

Place, publisher, year, edition, pages
2010. Vol. 97, no 1, 47-54 p.
Keyword [en]
Anorexia, Obesity, Paraventricular nucleus of the hypothalamus, Pituitary, Sugar, Taste aversion
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-135058DOI: 10.1016/j.pbb.2010.05.026ISI: 000284965800006PubMedID: 20595062OAI: oai:DiVA.org:uu-135058DiVA: diva2:374326
Available from: 2010-12-03 Created: 2010-12-03 Last updated: 2011-01-28Bibliographically approved

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