uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
Melt electrospinning of polycaprolactone and its blends with poly(ethylene glycol)
Uppsala University, Disciplinary Domain of Science and Technology, Biology, Biology Education Centre.
Show others and affiliations
2010 (English)In: Polymer international, ISSN 0959-8103, E-ISSN 1097-0126, Vol. 59, no 11, 1558-1562 p.Article in journal (Refereed) Published
Abstract [en]

Melt electrospinning is one aspect of electrospinning with relatively little published literature, although the technique avoids solvent accumulation and/or toxicity which is favoured in certain applications In the study reported, we melt-electrospun blends of poly(epsilon-caprolactone) (PCL) and an amphiphilic diblock copolymer consisting of poly(ethylene glycol) and PCL segments (PEG-block PCL) A custom-made electrospinning apparatus was built and various combinations of instrument parameters such as voltage and polymer feeding rate were investigated Pure PEG-block-PCL copolymer melt electrospinning did not result in consistent and uniform fibres due to the low molecular weight, while blends of PCL and PEG-block-PCL, for some parameter combinations and certain weight ratios of the two components, were able to produce continuous fibres significantly thinner (average diameter of ca 2 mu m) compared to pure PCL The PCL fibres obtained had average diameters ranging from 6 to 33 mu m and meshes were uniform for the lowest voltage employed while mesh uniformity decreased when the voltage was increased This approach shows that PCL and blends of PEG block-PCL and PCL can be readily processed by melt electrospinning to obtain fibrous meshes with varied average diameters and morphologies that are of interest for tissue engineering purposes.

Place, publisher, year, edition, pages
2010. Vol. 59, no 11, 1558-1562 p.
Keyword [en]
electrospinning, amphiphilic polymer, block copolymer, tissue engineering
National Category
Polymer Chemistry
URN: urn:nbn:se:uu:diva-135310DOI: 10.1002/pi.2954ISI: 000284023900013OAI: oai:DiVA.org:uu-135310DiVA: diva2:375693
Available from: 2010-12-08 Created: 2010-12-06 Last updated: 2010-12-08Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text
By organisation
Biology Education Centre
In the same journal
Polymer international
Polymer Chemistry

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 254 hits
ReferencesLink to record
Permanent link

Direct link