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The different levels of genetic diversity in sex chromosomes and autosomes
Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Ecology and Genetics, Evolutionary Biology.
2009 (English)In: Trends in Genetics, ISSN 0168-9525, E-ISSN 1362-4555, Vol. 25, no 6, 278-284 p.Article, review/survey (Refereed) Published
Abstract [en]

Sex chromosomes and autosomes differ in their effective population size, mutation and demography, all of which affect the relative level of genetic diversity within the genome. Moreover, natural selection acts differentially on the two chromosomal categories, for example, because recessive mutations are directly exposed to selection on the single X chromosome of males. Recent genome analyses reveal a heterogeneous picture of the sex-chromosome-to-autosome diversity ratio in different organisms. Reduced X chromosome diversity has been interpreted to reflect demographic features such as bottlenecks and male-biased dispersal, whereas more equal diversity in sex chromosomes and autosomes has been explained by polygynous mating systems.

Place, publisher, year, edition, pages
2009. Vol. 25, no 6, 278-284 p.
National Category
Biological Sciences
URN: urn:nbn:se:uu:diva-136628DOI: 10.1016/j.tig.2009.04.005ISI: 000267587000006PubMedID: 19481288OAI: oai:DiVA.org:uu-136628DiVA: diva2:377216
Available from: 2010-12-13 Created: 2010-12-13 Last updated: 2016-04-25Bibliographically approved

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