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Occupational risk factors for Wegener's granulomatosis: a case-control study
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
2010 (English)In: Annals of the Rheumatic Diseases, ISSN 0003-4967, E-ISSN 1468-2060, Vol. 69, no 4, 737-740 p.Article in journal (Refereed) Published
Abstract [en]

Background Wegener's granulomatosis is a systemic vasculitis of unknown aetiology. Previous studies have presented environmental exposures such as silica and farming as potential risk factors. Objective To investigate the potential risk for Wegener's granulomatosis associated with occupations involving contact with animals and various airway exposures, using a population-based approach. Methods In the Swedish Register of inpatient care 2288 cases with Wegener's granulomatosis were identified. Ten matched controls for every case were selected from the Swedish Population Register. By linking the cases and controls to the Swedish population censuses, information on employments before the diagnosis of Wegener's granulomatosis was collected. Relative risks were assessed as odds ratios using conditional logistic regression. Results Odds ratios for specific occupations ranged from 0.6 to 1.9, and centred symmetrically around 1. No statistically significant increased risk was noted for the investigated occupations.

Place, publisher, year, edition, pages
2010. Vol. 69, no 4, 737-740 p.
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Medical and Health Sciences
URN: urn:nbn:se:uu:diva-136819DOI: 10.1136/ard.2009.107953ISI: 000275723800023PubMedID: 19364729OAI: oai:DiVA.org:uu-136819DiVA: diva2:377542
Available from: 2010-12-14 Created: 2010-12-14 Last updated: 2010-12-14Bibliographically approved

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