uu.seUppsala University Publications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
A solid phase radioimmunoassay method for ferritin in serum using (125)I-labelled ferritin
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
1977 (English)In: Upsala Journal of Medical Sciences, ISSN 0300-9734, E-ISSN 2000-1967, Vol. 82, no 1, 15-19 p.Article in journal (Refereed) Published
Abstract [en]

A solid phase radioimmunoassay method for ferritin in serum was developed using ferritin conjugated with an (125)I-labelled ester. The method was based upon competitive inhibition utilizing the free antigen-binding sites of antibodies to ferritin bound to a ferritin which had been chemically coupled to insoluble polysaccharide particles. The method was evaluated with regard to specificity, sensitivity, precision and practicability and was found to be a robust method suitable for the assay of ferritin in human serum in clinical studies. There was a significant (P<0.001) difference between the ferritin levels in healthy men and women, mean values 100 and 66 arb U/l respectively. Male blood donors had significantly (P<0.002) lower ferritin levels in serum (mean 68.5 arb U/l) than other healthy men. Patients with iron overload or hepatic damage had high values, as expected, and the serum levels of ferritin reflected changes in iron deposits during phlebotomy and iron treatment in 3 healthy men.

Place, publisher, year, edition, pages
1977. Vol. 82, no 1, 15-19 p.
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-137051DOI: 10.3109/03009737709179053PubMedID: 20078269OAI: oai:DiVA.org:uu-137051DiVA: diva2:377833
Available from: 2010-12-15 Created: 2010-12-15 Last updated: 2017-12-11Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed
By organisation
Department of Medical Sciences
In the same journal
Upsala Journal of Medical Sciences
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 392 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf