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Serum ferritin and erythrocyte 2,3-DPG during quantitated phlebotomy and iron treatment
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
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1977 (English)In: Scandinavian journal of haematology, ISSN 0036-553X, Vol. 19, no 4, 327-333 p.Article in journal (Refereed) Published
Abstract [en]

Serum ferritin and erythrocyte 2,3-DPG levels were followed in 3 healthy males who were phlebotomized to iron depletion and a moderate anaemia. In 2 of the subjects, the expected rise in DPG levels was seen but not in the third, in spite of a Hb concentration of 95 g/1. Serum ferritin levels were found to reflect changes in iron stores, and subnormal serum ferritin indicated depleted iron stores. However, there was no correlation between pre-phlebotomy ferritin levels and calculated iron stores. The conclusion is that no fixed ratio can be established between serum ferritin and iron stores. A single ferritin value within the normal range does not tell how large iron stores a person has. Changes in an individual's iron stores can, however, be detected by repeated ferritin estimations.

Place, publisher, year, edition, pages
1977. Vol. 19, no 4, 327-333 p.
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-137052PubMedID: 918560OAI: oai:DiVA.org:uu-137052DiVA: diva2:377834
Available from: 2010-12-15 Created: 2010-12-15 Last updated: 2010-12-21Bibliographically approved

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