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Guidelines for the laboratory diagnosis of trichomoniasis in East European countries
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Bacteriology.
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2010 (English)In: Journal of the European Academy of Dermatology and Venereology, ISSN 0926-9959, E-ISSN 1468-3083, Vol. 24, no 10, 1125-1134 p.Article, review/survey (Refereed) Published
Abstract [en]

The laboratory diagnosis of sexually transmitted infections in many Eastern European countries remains suboptimal. The main objective of the present evidence-based guidelines is to provide comprehensive information regarding the laboratory diagnosis of infections caused by Trichomonas vaginalis in East European countries. In particular, the present guidelines recommend: (i) to encourage examination of the wet mounts of vaginal exudates, instead of stained smears, at all clinical settings; (ii) nucleic acid amplification tests (NAATs) or culture could be employed if no trichomonads are detected on microscopic examination of the wet preparation and there is a strong indication of infection and (iii) the use of NAATs is encouraged in screening, using non-invasive specimens, or high volume testing situations. In the absence of internationally recognized commercial NAAT systems, tests developed in-house should be validated using obtainable international standards and quality assured strictly. Individual East European countries may be required to make minor national adjustments to these guidelines as a result of lack of accessibility to some reagents or equipment, or laws in a specific country.

Place, publisher, year, edition, pages
2010. Vol. 24, no 10, 1125-1134 p.
Keyword [en]
Eastern Europe, guidelines, laboratory diagnosis, Trichomonas vaginalis
National Category
Dermatology and Venereal Diseases
URN: urn:nbn:se:uu:diva-137706DOI: 10.1111/j.1468-3083.2010.03601.xISI: 000281555800001OAI: oai:DiVA.org:uu-137706DiVA: diva2:379009
Available from: 2010-12-16 Created: 2010-12-15 Last updated: 2010-12-16Bibliographically approved

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