uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
The Anionic Boron Cluster (B(12)H(11)SH)(2-) as a Means To Trigger Release of Liposome Contents.
Show others and affiliations
2007 (English)In: ChemMedChed, ISSN 1860-7179, Vol. 2, no 1, 51-53 p.Article in journal (Refereed) Published
Abstract [en]

Triggered release. Liposomes are novel carriers for pharmaceutical agents and can be triggered to release their contents by the addition of B12H11SH, a compound in clinical use. As systemic toxicity is decreased relative to the free drug, liposomal drugs can therefore be administered in higher concentrations before dose-limiting side effects are met. Thus, liposome-encapsulated drugs may be of great value in the therapy of diseases.

Place, publisher, year, edition, pages
2007. Vol. 2, no 1, 51-53 p.
Keyword [en]
boranes, calorimetry, cellular toxicity, leakage, liposomes
National Category
Pharmaceutical Sciences
URN: urn:nbn:se:uu:diva-10148DOI: 10.1002/cmdc.200600227ISI: 000202946600004PubMedID: 17154431OAI: oai:DiVA.org:uu-10148DiVA: diva2:37916
Available from: 2007-02-28 Created: 2007-02-28 Last updated: 2011-04-19Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMedhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=17154431&dopt=Citation

Search in DiVA

By author/editor
Karlsson, GöranEdwards, Katarina
By organisation
Department of Physical and Analytical Chemistry
Pharmaceutical Sciences

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 364 hits
ReferencesLink to record
Permanent link

Direct link