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Maternal smoking does not affect fetal size as measured in the mid-second trimester
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health, Obstetrics and Gynaecology.
2007 (English)In: Acta Obstetricia et Gynecologica Scandinavica, ISSN 0001-6349, E-ISSN 1600-0412, Vol. 86, no 2, 156-160 p.Article in journal (Refereed) Published
Abstract [en]

Background. Cigarette smoking during pregnancy is causally related to birthweight, but we do not know whether fetal growth restriction is a continuous process or, if not, at what stage of pregnancy it affects weight gain. Material and methods. A random sample of para 1 and 2 mothers, drawn from the population of pregnant women in Bergen and Trondheim, Norway, and Uppsala, Sweden, were examined by a detailed questionnaire concerning smoking habits, menstrual history and pregnancy dating, and subjected to morphometric sonography of their fetuses in or around week 17. Of the 547 study participants, 31.9% were smokers. Gestational age was primarily determined by the last menstrual period [LMP], except in those with irregular cycles, and in 30 cases (6.6% of those with regular cycles) in whom the biparietal diameter [BPD]-determined age deviated >14 days from the LMP-based date. Results. The analysis did not reveal any statistically significant differences between the fetuses of non-smokers, light smokers (0-9 cigarettes per day) and heavy (10+ cigarettes per day) smokers, regarding BPD, mean abdominal diameter [MAD] femur length [FL], and a 'body contour index': [BPD+FL]MAD. Conclusion. Tobacco-induced fetal growth restriction probably begins after gestational week 17.

Place, publisher, year, edition, pages
2007. Vol. 86, no 2, 156-160 p.
Keyword [en]
Pregnancy, smoking, ultrasonography, fetus, anthropometry, biparietal diameter, abdominal circumference, femur length
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-10242DOI: 10.1080/00016340600984696ISI: 000244922700005PubMedID: 17364277OAI: oai:DiVA.org:uu-10242DiVA: diva2:38010
Available from: 2007-03-05 Created: 2007-03-05 Last updated: 2011-02-11Bibliographically approved

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Lindmark, Gunilla
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