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Radionuclide Hysterosalpingography Is Not a Reliable Tool for Investigation of Fallopian Tube Transport: A Controlled Randomized Study Using Particles of Two Sizes during Three Different Parts of the Menstrual Cycle
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health, Obstetrics and Gynaecology. (Klinisk och experimentell reproduktionsbiologi/Olovsson)
Dept of Women´s and Children´s Health, Karolinska institutet.
Dept of Radiology, Karolinska University Hospital, Stockholm, Sweden.
Dept of Women´s and Children´s Health, Karolinska institutet.
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2011 (English)In: Gynecologic and Obstetric Investigation, ISSN 0378-7346, E-ISSN 1423-002x, Vol. 72, no 1, 20-24 p.Article in journal (Refereed) Published
Abstract [en]

Background/Aims: Earlier studies with radionuclide hysterosalpingography (RN-HSG) using either small or large particles have shown different results. Some studies have questioned the clinical relevance of RN-HSG. The aim of this study was to evaluate the RN-HSG method using two different sizes of radio-labelled particles during different parts of the menstrual cycle. Methods: Ten healthy women, 28–40 years of age (mean 34.5), with proven fertility, regular menstrual cycle, not using oral contraceptives and due to undergo laparoscopic sterilization, were randomized to RN-HSG after deposition of a solution with either small Albures or large MAASOL, 99mTc-radio-labelled particles into the cervix uteri. Investigations were, for every patient, performed during the follicular, peri-ovulatory and mid-luteal parts of the menstrual cycle. Transport of radioactivity from cervix to uterus and Fallopian tubes was evaluated. Results: The RN-HSG investigations could not show any difference between the two different sizes of radio-labelled particles. Transport of radioactivity to the Fallopian tube was seen only in some cases and most frequently during the peri-ovulatory period. Conclusion: We found the RN-HSG investigations inconclusive. The RN-HSG method does not seem to be a reliable tool for the investigation of Fallopian tube transport.

Place, publisher, year, edition, pages
2011. Vol. 72, no 1, 20-24 p.
Keyword [en]
Fallopian tube, Radionuclide hysterosalpingography, Tubal infertility, Tubal investigation, Tubal transport
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-138953DOI: 10.1159/000321795ISI: 000293591700005OAI: oai:DiVA.org:uu-138953DiVA: diva2:380413
Available from: 2010-12-21 Created: 2010-12-21 Last updated: 2011-09-06Bibliographically approved

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Wånggren, Kjell
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