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Analysis of the essential oil from the aerial parts of Psoralea pubescence (Miq.) Standl and its antibacterial activity
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Pharmacy, Department of Medicinal Chemistry, Division of Pharmacognosy.
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2010 (English)In: Medicinal Chemistry Research, ISSN 1054-2523, E-ISSN 1554-8120, Vol. 19, no 9, 1036-1042 p.Article in journal (Refereed) Published
Abstract [en]

The essential oil from aerial parts of Psoralea pubescence (Miq.) Standl (Leguminoseae) was analyzed by gas chromatography (GC) and GC/mass spectroscopy systems. The major components identified were psoralen (24.8%), bakuchiol (21.3%), beta-caryophyllene (8.5%), germacrene D (6.8%), and alpha-humulene (4.6%). The major volatiles released by beta-glucosidase treatment of the aqueous plant residue were delta-pinene (28.3%), germacrene D (13.6%), and tricyclene (10.2%). The oil showed significant antibacterial activity against Staphylococcus aureus, Escherichia coli, Klebsiella pneumonia, and Pseudomonas aeruginosa, while the beta-glucosidase-liberated fraction was inactive.

Place, publisher, year, edition, pages
2010. Vol. 19, no 9, 1036-1042 p.
Keyword [en]
Psoralea pubescence, Leguminosae, Essential oil composition, Thymol, Carvacrol, Pulegone, Volatiles, Antimicrobial activity, Gas chromatography-mass spectroscopy
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-139264DOI: 10.1007/s00044-009-9249-xISI: 000284432000002OAI: oai:DiVA.org:uu-139264DiVA: diva2:380926
Available from: 2010-12-22 Created: 2010-12-22 Last updated: 2010-12-22Bibliographically approved

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