uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
A New Era in the Diagnosis and Treatment of Breast Cancer
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Oncology, Radiology and Clinical Immunology, Radiology.
2010 (English)In: The Breast Journal, ISSN 1075-122X, E-ISSN 1524-4741, Vol. 16, S2-S4 p.Article in journal (Refereed) Published
Abstract [en]

Randomized controlled mammography screening trials and the evaluation of service screening have unequivocally proven that regular mammography screening significantly reduces mortality from breast cancer. This evidence contradicts the theory of Fisher, claiming that breast cancer is a systemic disease from its inception and undermines the justification for systemic therapy in most screen-detected cancers, because they are still localized to the breast and can be cured by local treatment alone. When high quality mammographic screening is offered at regular intervals to 40- to 74-year-old women, over 50% of the invasive cancers will be detected in the size range of 1-14 mm, fewer than 20% will be axillary node positive, and only about 20% will be poorly differentiated. This predominance of early-stage disease has created a revolutionary new era for those involved in the diagnosis and treatment of patients with breast cancer.

Place, publisher, year, edition, pages
2010. Vol. 16, S2-S4 p.
Keyword [en]
breast cancer, early detection, mammography screening, multifocal breast cancer, randomized controlled trial
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-139354DOI: 10.1111/j.1524-4741.2010.00992.xISI: 000283986900002OAI: oai:DiVA.org:uu-139354DiVA: diva2:381050
Available from: 2010-12-23 Created: 2010-12-23 Last updated: 2010-12-23Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text
By organisation
In the same journal
The Breast Journal
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 190 hits
ReferencesLink to record
Permanent link

Direct link