uu.seUppsala University Publications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Ventilation practices in the neonatal intensive care unit: a cross-sectional study
Show others and affiliations
2010 (English)In: Journal of Pediatrics, ISSN 0022-3476, E-ISSN 1097-6833, Vol. 157, no 5, 767-U101 p.Article in journal (Refereed) Published
Abstract [en]

Objective To assess current ventilation practices in newborn infants. 

Study design We conducted a 2-point cross-sectional study in 173 European neonatal intensive care units, including 535 infants (mean gestational age 28 weeks and birth weight 1024 g). Patient characteristics, ventilator settings, and measurements were collected bedside from endotracheally ventilated infants. 

Results A total of 457 (85%) patients were conventionally ventilated. Time cycled pressure-limited ventilation was used in 59% of these patients, most often combined with synchronized intermittent mandatory ventilation (51%). Newer conventional ventilation modes like volume targeted and pressure support ventilation were used in, respectively, 9% and 7% of the patients. The mean tidal volume, measured in 84% of the conventionally ventilated patients, was 5.7 +/- 2.3 ml/kg. The mean positive end-expiratory pressure was 4.5 +/- 1.1 cmH(2)O and rarely exceeded 7 cmH(2)O. 

Conclusions Time cycled pressure-limited ventilation is the most commonly used mode in neonatal ventilation. Tidal volumes are usually targeted between 4 to 7 mL/kg and positive end-expiratory pressure between 4 to 6 cmH(2)O. Newer ventilation modes are only used in a minority of patients. (J Pediatr 2010; 157:767-71).

Place, publisher, year, edition, pages
2010. Vol. 157, no 5, 767-U101 p.
National Category
Pediatrics
Identifiers
URN: urn:nbn:se:uu:diva-139515DOI: 10.1016/j.jpeds.2010.05.043ISI: 000283045900019PubMedID: 20619854OAI: oai:DiVA.org:uu-139515DiVA: diva2:381493
Note

Co-author: Richard Sindelar, Uppsala universitet, Institutionen för kvinnors och barns hälsa, forskargrupp Perinatal, neonatal och barnkardiologisk forskning/Jonzon, ingår i Neovent Study Group.

A list of Neovent Study Group members is available in the Appendix.

Available from: 2010-12-27 Created: 2010-12-27 Last updated: 2017-12-11Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Authority records BETA

Sindelar, Richard

Search in DiVA

By author/editor
Sindelar, Richard
By organisation
Pediatrics
In the same journal
Journal of Pediatrics
Pediatrics

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 387 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf