Antibodies to several citrullinated antigens are enriched in the joints of rheumatoid arthritis patients
2010 (English)In: Arthritis and Rheumatism, ISSN 0004-3591, E-ISSN 1529-0131, Vol. 62, no 1, 44-52 p.Article in journal (Refereed) Published
MCV and CCP positivity represent a similar subset of RA patients, whereas ACPAs with different fine specificities fall into subgroups of anti-CCP+/anti-MCV+ patients. The levels of all specific ACPAs were elevated in synovial fluid, suggesting that there is local antibody production and/or retention of ACPAs at the site of inflammation governed by RA-predisposing genes.
Place, publisher, year, edition, pages
2010. Vol. 62, no 1, 44-52 p.
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:uu:diva-140009DOI: 10.1002/art.25036ISI: 000279275700006PubMedID: 20039432OAI: oai:DiVA.org:uu-140009DiVA: diva2:382722