Luteal phase progesterone increases live birth rate after frozen embryo transfer
2011 (English)In: Fertility and Sterility, ISSN 0015-0282, Vol. 95, no 2, 534-537 p.Article in journal (Refereed) Published
OBJECTIVE: To see if progesterone support has a beneficial effect on live birth rate after frozen embryo transfer in natural cycles. DESIGN: Prospective randomized controlled trial. SETTING: University-based hospital. SUBJECT(S): Four hundred thirty-five women undergoing embryo transfer in natural cycles. INTERVENTION(S): The women received either vaginal progesterone, 400 mg twice a day from the day of embryo transfer in natural cycles, or no progesterone support. MAIN OUTCOME MEASURE(S): Live birth rate, biochemical pregnancy rate, pregnancy rate, and spontaneous abortion rate. RESULT(S): Live birth rate were significantly greater in women receiving vaginal progesterone as luteal phase support after frozen-thawed embryo transfer in natural cycles compared with those who did not take progesterone. There were no differences in biochemical pregnancy rate, pregnancy rate, or spontaneous abortion rate. CONCLUSION(S): Progesterone supplementation improves live birth rate after embryo transfer in natural cycles.
Place, publisher, year, edition, pages
2011. Vol. 95, no 2, 534-537 p.
frozen embryo transfer, live birth rate, natural menstrual cycle, pregnancy rate, Progesterone
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:uu:diva-140104DOI: 10.1016/j.fertnstert.2010.05.019ISI: 000286419000023PubMedID: 20579989OAI: oai:DiVA.org:uu-140104DiVA: diva2:382936