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Synthesis and Characterization of a Multi Ring-Fused 2-Pyridone-Based Fluorescent Scaffold
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2010 (English)In: European Journal of Organic Chemistry, ISSN 1434-193X, E-ISSN 1099-0690, no 32, 6171-6178 p.Article in journal (Refereed) Published
Abstract [en]

A series of compounds based on a novel fluorescent scaffold have been synthesized. Most of the compounds displayed high quantum yields of fluorescence and unusually long fluorescence lifetimes. HeLa cells were treated with one of the compounds and its use as a fluorescent dye was demonstrated with fluorescence confocal microscopy.

Place, publisher, year, edition, pages
2010. no 32, 6171-6178 p.
Keyword [en]
Medicinal chemistry, Heterocycles, Luminescence, Fluorescent probes
National Category
Chemical Sciences
URN: urn:nbn:se:uu:diva-140956DOI: 10.1002/ejoc.201000796ISI: 000285041500007OAI: oai:DiVA.org:uu-140956DiVA: diva2:384738
Available from: 2011-01-10 Created: 2011-01-10 Last updated: 2011-01-10Bibliographically approved

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Clinical Pharmacology
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