Inflammation in Arthropods
2010 (English)In: Current pharmaceutical design, ISSN 1381-6128, E-ISSN 1873-4286, Vol. 16, no 38, 4166-4174 p.Article, review/survey (Refereed) Published
The inflammatory process in arthropods includes primarily the recruitment of circulating hemocytes to wounds or sites of microbial infections. Melanization, capsule formation and clotting reactions will finally result in the sealing of wounds. In this review we will focus on recent research about hemolymph clotting and melanization reactions, and the recruitment of hemocytes to wounds and infections. We further describe in more detail new knowledge about crustacean hematopoiesis that is crucial for hemocyte recruitment to the site of an infection and there develop an inflammatory response Moreover, we pay special attention to the gut as an important route of infection in arthropods. Since the gastrointestinal tract provides a first line of defense and regulation of the indigenous bacteria and the intestine often harbors loads of potential pathogenic microorganisms. Therefore the integrity of intestinal epithelium and to maintain the correct flora is crucial to animal health.
Place, publisher, year, edition, pages
2010. Vol. 16, no 38, 4166-4174 p.
Coagulation, hematopoiesis, hemocyte, innate immunity, inflammation, injury, intestinal immunity, ProPO system, wound healing
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:uu:diva-141551ISI: 000287358200003PubMedID: 21184661OAI: oai:DiVA.org:uu-141551DiVA: diva2:385775