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Thyroid hormons and thyromimetics
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Pharmacy, Department of Medicinal Chemistry, Organic Pharmaceutical Chemistry.
2010 (English)In: Burger's Medicinal Chemistry, Drug Discovery and Development / [ed] Donald J. Abraham, David P. Rotella, John Wiley and Sons , 2010, 7, , 50 p.189-237 p.Chapter in book (Other academic)
Abstract [en]

This chapter will provide an overview on the recent design principles and structure–activity relationship of thyroid hormones and thyromimetics. The prospects for the treatment of metabolic diseases, hypo- and hyperthyroidism, and cardiac disease with pharmacologically selective thyromimetics are considerable if cardiovascular acceleration and other adverse events can be avoided.

Place, publisher, year, edition, pages
John Wiley and Sons , 2010, 7. , 50 p.189-237 p.
Keyword [en]
cardiac disease, metabolic diseases, SAR, thyroid disease, thyromimetics
National Category
Medical and Health Sciences Pharmaceutical Sciences
URN: urn:nbn:se:uu:diva-141804DOI: 10.1002/0471266949.bmc052.pub2ISBN: 9780471266945OAI: oai:DiVA.org:uu-141804DiVA: diva2:386248
Available from: 2011-01-12 Created: 2011-01-12 Last updated: 2011-01-25Bibliographically approved

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