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Radical scavengers: a remedy for presbyacusis. A pilot study
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences. (Ear-Nose-Throat)
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences. (Ear-Nose-Throat)
2005 (English)In: Acta Oto-Laryngologica, ISSN 0001-6489, E-ISSN 1651-2251, Vol. 125, no 12, 1290-5 p.Article in journal (Refereed) Published
Abstract [en]

CONCLUSION: The results of this study suggest that treatment with radical scavengers has the potential to become an effective new therapy for presbyacusis. OBJECTIVE: To assess the efficacy of treatment with the radical scavengers rebamipide and vitamin C for presbyacusis. MATERIAL AND METHODS: Rebamipide (300 mg/day) and vitamin C (600 mg/day) were taken orally for at least 8 weeks by 23 patients with presbyacusis. RESULTS: Hearing levels after treatment were significantly improved at 125, 250, 500 and 8000 Hz but unchanged at 1000, 2000 and 4000 Hz.

Place, publisher, year, edition, pages
2005. Vol. 125, no 12, 1290-5 p.
Keyword [en]
Aged, Aged; 80 and over, Alanine/*analogs & derivatives/therapeutic use, Ascorbic Acid/*therapeutic use, Audiometry, Dose-Response Relationship; Drug, Drug Administration Schedule, Female, Follow-Up Studies, Free Radical Scavengers/*therapeutic use, Humans, Male, Pilot Projects, Presbycusis/*diagnosis/*drug therapy, Probability, Quinolones/*therapeutic use, Risk Assessment, Severity of Illness Index, Treatment Outcome
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-10936PubMedID: 16303676OAI: oai:DiVA.org:uu-10936DiVA: diva2:38704
Available from: 2008-02-19 Created: 2008-02-19 Last updated: 2017-12-11Bibliographically approved

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Anniko, Matti

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