Assessment of Health-Related Quality of Life and Patient Satisfaction in Children and Adolescents with Growth Hormone Deficiency or Idiopathic Short Stature - Part 1: A Critical Evaluation of Available Tools
2009 (English)In: Hormone Research, ISSN 0301-0163, E-ISSN 1423-0046, Vol. 72, no 2, 65-73 p.Article, review/survey (Refereed) Published
The concept of health-related quality of life (HrQoL) reflects the subjective perception of health and includes aspects of well-being and functioning in physical, emotional, mental and social life domains. Nowadays, HrQoL has become a relevant treatment outcome from epidemiological and clinical perspectives and is also broadly employed in health economic analyses. To assess HrQoL generic as well as condition-specific instruments are used. The former are applicable to a wide range of health conditions and aim at measuring HrQoL across different conditions. The latter focus on capturing the impact of a specific disease. Although HrQoL research in adults is now well-advanced, there are still open questions regarding how to assess HrQoL in pediatric conditions, such as short stature. Eight generic (one chronic-generic) and seven condition-specific (one treatment-specific) instruments used in HrQoL research in short stature of youth are described. Additionally, this mini review identifies a need for further research and indicates potential directions.
Place, publisher, year, edition, pages
2009. Vol. 72, no 2, 65-73 p.
Growth hormone deficiency, Health-related quality of life, Short stature, idiopathic
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:uu:diva-142203DOI: 10.1159/000232158ISI: 000269139300001OAI: oai:DiVA.org:uu-142203DiVA: diva2:387146