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The myxoid/round cell liposarcoma fusion oncogene FUS-DDIT3 and the normal DDIT3 induce a liposarcoma phenotype in transfected human fibrosarcoma cells.
Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Genetics and Pathology. Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Genetics and Pathology.
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2006 (English)In: Am J Pathol, ISSN 0002-9440, Vol. 168, no 5, 1642-53 p.Article in journal (Refereed) Published
Place, publisher, year, edition, pages
2006. Vol. 168, no 5, 1642-53 p.
Keyword [en]
Adipogenesis, Animals, Cluster Analysis, Down-Regulation, Female, Fibrosarcoma/*blood supply/metabolism, Gene Expression Regulation; Neoplastic, Humans, Liposarcoma; Myxoid/*blood supply/metabolism, Mice, Mice; SCID, Oligonucleotide Array Sequence Analysis, Oncogene Proteins; Fusion/physiology, RNA-Binding Protein FUS/genetics/metabolism/*physiology, Transcription Factor CHOP/metabolism/*physiology, Transfection, Up-Regulation
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URN: urn:nbn:se:uu:diva-11040PubMedID: 16651630OAI: oai:DiVA.org:uu-11040DiVA: diva2:38808
Available from: 2007-05-14 Created: 2007-05-14 Last updated: 2011-01-11

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