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Microfluidic high viability separation of neural cells
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Microsystems Technology.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience.
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Microsystems Technology.
2009 (English)In: 2009 4TH IEEE INTERNATIONAL CONFERENCE ON NANO/MICRO ENGINEERED AND MOLECULAR SYSTEMS, VOLS 1 AND 2, Shenzhen, CHINA, JAN 05-08, 2009, IEEE , 2009, 1079-1083 p.Conference paper, Published paper (Refereed)
Abstract [en]

A novel microfluidic platform is presented for sorting by size dissociated neurons, glia and stem cells from biopsies of the central nerve system. A highly biocompatible aqueous polymer solution was used in hydrodynamic spreading controlled cell separation. Before cell separation, particles were used for demonstration. To verify the results the fractions were studied using flow cytometry. Further, they were cultured and differentiated. The study indicated that the technique is ready for biological study and that it has a high potential for applications in neural cell regeneration therapy.

Place, publisher, year, edition, pages
IEEE , 2009. 1079-1083 p.
Keyword [en]
microfluidic, high viability, separation, neural cells
National Category
Engineering and Technology
Identifiers
URN: urn:nbn:se:uu:diva-137688ISI: 000273161500248ISBN: 978-1-4244-4629-2 (print)OAI: oai:DiVA.org:uu-137688DiVA: diva2:393404
Conference
4th IEEE International Conference of Nano/Micro Engineered and Molecular Systems, Shenzhen, CHINA, JAN 05-08, 2009
Available from: 2011-01-31 Created: 2010-12-15 Last updated: 2016-04-14Bibliographically approved

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Wu, ZhigangHjort, Klas

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