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Acute Effects of Some Volatile Organic Compounds Emitted From Waters-Based Paints
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Occupational and Environmental Medicine. (Eva Vingård)
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Occupational and Environmental Medicine. (Eva Vingård)
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2007 (English)In: Journal of Occupational and Environmental Medicine, ISSN 1076-2752, E-ISSN 1536-5948, Vol. 49, no 8, 880-889 p.Article in journal (Refereed) Published
Abstract [en]

OBJECTIVE: Acute effects during controlled exposure to some of the volatile organic compounds emitted from water-based paints were evaluated. METHODS: Healthy volunteers (10 atopics, 10 nonatopics, and 10 painters) were exposed to a mixture of propyleneglycol, texanol, diethyleneglycol monoethylether, diethyleneglycol monobutyl ether, and dipropyleneglycol monomethyl ether at a total concentration of 35 mg/m3 (G), a mixture of G and ammonia (15 mg/m3) (GA), and clean air (C). RESULTS: Subjective ratings of irritation in eyes, nose, throat, and dyspnea were significantly higher during the G and GA conditions, when compared with during the C condition. Nasal mucosal swelling was observed after G but not after GA exposure. No effects of the exposure on the pulmonary function, markers of inflammation in nasal lavages, and renal function in urine were seen. CONCLUSION: Exposure to G and GA caused mild irritation in eyes, nose, and airways.

Place, publisher, year, edition, pages
2007. Vol. 49, no 8, 880-889 p.
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Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-11656DOI: 10.1097/JOM.0b013e3181161cedISI: 000248772000009PubMedID: 17693786OAI: oai:DiVA.org:uu-11656DiVA: diva2:39425
Available from: 2007-10-10 Created: 2007-10-10 Last updated: 2017-12-11Bibliographically approved

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Wieslander, GunillaNorbäck, Dan

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