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The IMRT information process-mastering the degrees of freedom in external beam therapy
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Oncology, Radiology and Clinical Immunology.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Oncology, Radiology and Clinical Immunology.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Oncology, Radiology and Clinical Immunology.
2006 (English)In: Physics in Medicine and Biology, ISSN 0031-9155, E-ISSN 1361-6560, Vol. 51, no 13, R381-402 p.Article in journal (Refereed) Published
Abstract [en]

The techniques and procedures for intensity-modulated radiation therapy (IMRT) are reviewed in the context of the information process central to treatment planning and delivery of IMRT. A presentation is given of the evolution of the information based radiotherapy workflow and dose delivery techniques, as well as the volume and planning concepts for relating the dose information to image based patient representations. The formulation of the dose shaping process as an optimization problem is described. The different steps in the calculation flow for determination of machine parameters for dose delivery are described starting from the formulation of optimization objectives over dose calculation to optimization procedures. Finally, the main elements of the quality assurance procedure necessary for implementing IMRT clinically are reviewed.

Place, publisher, year, edition, pages
2006. Vol. 51, no 13, R381-402 p.
Keyword [en]
Animals, Computer Simulation, Equipment Design, Forecasting, Humans, Models; Biological, Neoplasms/*radiotherapy, Radiometry/*methods/trends, Radiotherapy Dosage, Radiotherapy Planning; Computer-Assisted/*methods/trends, Radiotherapy; Conformal/*methods/trends
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-12113DOI: 10.1088/0031-9155/51/13/R22PubMedID: 16790914OAI: oai:DiVA.org:uu-12113DiVA: diva2:39882
Available from: 2007-11-27 Created: 2007-11-27 Last updated: 2017-12-11Bibliographically approved

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Ahnesjö, AndersIsacsson, UlfMontelius, Anders

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