Lung transplantation in patients with cystic fibrosis and Mycobacterium abscessus infection
2010 (English)In: Journal of Cystic Fibrosis, ISSN 1569-1993, E-ISSN 1873-5010, Vol. 9, no 4, 272-276 p.Article in journal (Refereed) Published
Mycobacterium abscessus lung disease is difficult to treat and has been considered a strong relative contraindication to lung transplantation. We performed double lung transplantation in three cystic fibrosis patients with ongoing, and a fourth with recent treatment for Mycobacterium abscessus lung infection. Despite prolonged antibiotic courses and adjustment of immunosuppressive therapy the first three patients developed skin infection and abscesses. At follow-up after 1, 3, 5 and 7 years respectively no patient had evidence of M abscessus infection and all had stable lung function. Lung transplantation in patients with M abscessus lung infection is feasible but may involve severe complications.
Place, publisher, year, edition, pages
2010. Vol. 9, no 4, 272-276 p.
Cystic fibrosis, Lung transplantation, Mycobacterium Complication, Abscess
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:uu:diva-147198DOI: 10.1016/j.jcf.2010.03.008ISI: 000280009500007OAI: oai:DiVA.org:uu-147198DiVA: diva2:400286