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Multiple transport mechanisms involved in the intestinal absorption and first-pass extraction of fexofenadine.
Uppsala University, Medicinska vetenskapsområdet, Faculty of Pharmacy, Department of Pharmacy.
Uppsala University, Medicinska vetenskapsområdet, Faculty of Pharmacy, Department of Pharmacy.
Faculty of Medicine, Department of Surgical Sciences. Loc-I-Gut-group.
Department of Medicinal Chemistry. Analyc.
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2003 (English)In: Clin Pharmacol Ther, ISSN 0009-9236, Vol. 74, no 5, 423-36 p.Article in journal (Refereed) Published
Place, publisher, year, edition, pages
2003. Vol. 74, no 5, 423-36 p.
Keyword [en]
Adult, Algorithms, Anti-Allergic Agents/*pharmacokinetics, Area Under Curve, Biological Availability, Calcium Channel Blockers/pharmacology, Chromatography; High Pressure Liquid, Female, Humans, Intestinal Absorption/drug effects, Intestines/blood supply, Jejunum/blood supply/metabolism, Male, Membrane Transport Modulators, Membrane Transport Proteins/antagonists & inhibitors/*metabolism, Regional Blood Flow/physiology, Spectrophotometry; Ultraviolet, Terfenadine/*analogs & derivatives/*pharmacokinetics, Verapamil/pharmacology
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URN: urn:nbn:se:uu:diva-12326PubMedID: 14586383OAI: oai:DiVA.org:uu-12326DiVA: diva2:40095
Available from: 2007-12-12 Created: 2007-12-12 Last updated: 2011-01-13

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Knutson, LarsHedeland, MikaelBondesson, UlfLennernäs, Hans

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