Development of pinene-derived N,P ligands and their utility in catalytic asymmetric hydrogenation
2007 (English)In: Dalton Transactions, ISSN 1477-9226, E-ISSN 1477-9234, no 47, 5603-5610 p.Article in journal (Refereed) Published
New diastereomeric N,P-ligands, derived from the natural product (+)--pinene, have been synthesized and evaluated in iridium-catalyzed asymmetric hydrogenation. The ligands are tetrahydroquinoline derivatives synthesized directly from commercially available -pinene utilizing resolution or recrystallization to separate diastereomers. In reduction of a range of different trisubstituted alkenes the catalysts express very different activities ranging from no activity to high activity. One of the catalysts gives good ee values for some substrates.
Place, publisher, year, edition, pages
2007. no 47, 5603-5610 p.
IdentifiersURN: urn:nbn:se:uu:diva-12344DOI: 10.1039/b713257nISI: 000251269100016OAI: oai:DiVA.org:uu-12344DiVA: diva2:40113