uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
Bone metabolism analyzed by PET and DXA following revision THA using a distally fixed stem: A pilot study
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm , Centre for Research and Development, Gävleborg.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Radiology, Oncology and Radiation Science, Section of Nuclear Medicine and PET.
2011 (English)In: HIP International, ISSN 1120-7000, Vol. 21, no 1, 30-38 p.Article in journal (Refereed) Published
Abstract [en]

In a pilot study we analyzed bone remodeling using F-18-PET (positon emission tomography) scanning or DXA (dual-energy x-ray absorptiometry) in 3 patient groups, one with a loose femoral stem and 2 after revision using a modular stem (MP). In loose implants (group 1), bone formation activity compared to the contralateral healthy femur was 261 %. In the proximal part of the femur bone formation was increased by 253 % one week after revision (group 2) and did not normalize within 1 year. In the distal region it decreased to normal after one year. In the second revision group DXA showed decreased bone mineral density at 6 and 24 months (group 3). The PET technique provided evidence of bone healing despite osteolysis and prosthetic loosening which continued after revision. Decreasing BMD after revision in the third group is multifactorial, but suggests that despite intensive bone formation resorption was still higher.

Place, publisher, year, edition, pages
2011. Vol. 21, no 1, 30-38 p.
Keyword [en]
DXA, Osteolysis, Positron emission tomography, Revision, RSA, Total hip arthroplasty
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-148618DOI: 10.5301/HIP.2011.6304ISI: 000287485500005PubMedID: 21298623OAI: oai:DiVA.org:uu-148618DiVA: diva2:402454
Available from: 2011-03-08 Created: 2011-03-08 Last updated: 2012-03-12Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Ullmark, GöstaSörensen, Jens
By organisation
Centre for Research and Development, GävleborgSection of Nuclear Medicine and PET
In the same journal
HIP International
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 195 hits
ReferencesLink to record
Permanent link

Direct link