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Trends in the bioanalytical applications of microfluidic electrocapture
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Biosciences. (Laboratory for Biological and Medical Mass Spectrometry)
2011 (English)In: Analytical and Bioanalytical Chemistry, ISSN 1618-2642, E-ISSN 1618-2650, Vol. 399, no 1, 191-195 p.Article in journal (Other academic) Published
Abstract [en]
Downscaled analytical tools for sample preparation have offered benefits such as higher throughput, easier automation and lower sample/reagent consumption. Microfluidic electrocapture, which is a newly developed sample preparation/manipulation system, uses an electric field to trap and separate charged species without using any solid sorbent. The feasibility of using microfluidic electrocapture is reported for separation, clean-up, concentration, microreactions and complexation studies of proteins, peptides and other biologically important biomolecules. The instrumentation and applications of microfluidic electrocapture are reviewed and an overview is provided of future perspectives offered by the current and envisaged platforms.
Place, publisher, year, edition, pages
2011. Vol. 399, no 1, 191-195 p.
Keyword [en]
Sample preparation, Mass spectrometry, Microfluidic, Electrocapture
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-148663DOI: 10.1007/s00216-010-4092-yISI: 000285781200019PubMedID: 20717653OAI: oai:DiVA.org:uu-148663DiVA: diva2:402644
Available from: 2011-03-09 Created: 2011-03-09 Last updated: 2017-12-11Bibliographically approved

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