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Organ-Specific Tubular and Collagen-Based Composite Scaffolds
Uppsala University, Disciplinary Domain of Science and Technology, Chemistry, Department of Materials Chemistry, Polymer Chemistry.
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2011 (English)In: Tissue Engineering Part C: Methods, ISSN 1937-3384, Vol. 17, no 3, 327-335 p.Article in journal (Refereed) Published
Abstract [en]

The body contains a number of organs characterized by a tubular shape. In this study, we explored several methodologies for the construction of collagenous tubular scaffolds and films with defined (ultra) structure, length, diameter, orientation, and molecular composition. Standardization of molding, casting, freezing, and lyophilizing techniques using inexpensive materials and methods resulted in controllable fabrication of a wide variety of tubular and tissue-specific tubular scaffolds and films. Analysis included immunohistochemical and (ultra) structural examination. Handling and suturability were found adequate for tissue engineering applications.

Place, publisher, year, edition, pages
2011. Vol. 17, no 3, 327-335 p.
National Category
Medical and Health Sciences Polymer Chemistry
Research subject
Chemistry with specialization in Polymer Chemistry
URN: urn:nbn:se:uu:diva-148984DOI: 10.1089/ten.tec.2010.0269ISI: 000287799400008PubMedID: 20929288OAI: oai:DiVA.org:uu-148984DiVA: diva2:403682
Available from: 2011-03-14 Created: 2011-03-14 Last updated: 2011-11-29Bibliographically approved

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