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Measurement of direct ethanol metabolites suggests higher rate of alcohol use among pregnant women than found with the AUDIT: a pilot study in a population-based sample of Swedish women
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health, Obstetrics and Gynaecology.
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2008 (English)In: American Journal of Obstetrics and Gynecology, ISSN 0002-9378, E-ISSN 1097-6868, Vol. 198, no 4, 407.e1- p.Article in journal (Refereed) Published
Abstract [en]

OBJECTIVES: The objective of the study was to investigate whether biomarkers of alcohol consumption would provide additional information to the use of a validated alcohol questionnaire in pregnant women. STUDY DESIGN: One hundred three pregnant women were included in the study. The women completed the Alcohol Use Disorders Identification Test (AUDIT) questionnaire, and a urine and hair sample was collected. The urine samples were used for determination of ethyl glucuronide (EtG) and ethyl sulfate and the hair samples for EtG and fatty acid ethyl esters (FAEE). RESULTS: Twenty-six women (25.2%) were identified as possible alcohol consumers by the combined use of AUDIT and direct ethanol metabolites. Seven subjects had EtG or FAEE levels in hair highly suspicious of heavy drinking, but only 1 of these were positive according to the AUDIT questionnaire CONCLUSION: The combined use of the AUDIT questionnaire and direct ethanol metabolites appear to identify more potential alcohol consumers among pregnant women than does the sole use of the AUDIT questionnaire.

Place, publisher, year, edition, pages
2008. Vol. 198, no 4, 407.e1- p.
Keyword [en]
alcohol, alcohol use disorders identification test, direct ethanol metabolites, pregnancy
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-149837DOI: 10.1016/j.ajog.2007.10.801ISI: 000254980200020OAI: oai:DiVA.org:uu-149837DiVA: diva2:405974
Available from: 2011-03-24 Created: 2011-03-24 Last updated: 2011-03-24Bibliographically approved

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