Recent advances in the genetics of autoimmune diseases
2007 (English)In: AUTOIMMUNITY, PT B: NOVEL APPLICATIONS OF BASIC RESEARCH / [ed] Gershwin ME, Shoenfeld Y, 2007, Vol. 1110, 1-9 p.Conference paper (Refereed)
Autoimmune diseases in general are complex genetic diseases where genes and environment interact in unknown ways. In recent years technologies have advanced our knowledge and new genes are being identified very rapidly. We can expect that most genes of major importance for the various autoimmune diseases will be discovered in the coming 5 years. The real challenge comes when we try to understand the mechanisms through which these genes confer disease susceptibility and how the interaction with environment takes place such that clinical expression of the disease results.
Place, publisher, year, edition, pages
2007. Vol. 1110, 1-9 p.
, Annals of the New York Academy of Sciences, ISSN 0077-8923 ; 1110
systemic lupus erythematosus, inflammatory bowel disease, type 1 diabetes mellitus, rheumatoid arthritis, linkage, genetic association, single nucleotide polymorphisms, chromosomes, copy number variation
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:uu:diva-12898DOI: 10.1196/annals.1423.001ISI: 000250428100002PubMedID: 17911414ISBN: 978-1-57331-709-2OAI: oai:DiVA.org:uu-12898DiVA: diva2:40668
5th International Congress on Autoimmunity Sorrento, ITALY, NOV 29-DEC 03, 2006