uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
Does chemotherapy prior to liver resection increase the potential for cure in patients with metastatic colorectal cancer?: A report from the European Colorectal Metastases Treatment Group
Show others and affiliations
2007 (English)In: European Journal of Cancer, ISSN 0959-8049, E-ISSN 1879-0852, Vol. 43, no 14, 2037-2045 p.Article, review/survey (Refereed) Published
Abstract [en]

Liver resection offers the only chance of cure for patients with advanced colorectal cancer (CRC). Typically, the 5-year survival rates following liver resection range from 25% to 40%. Unfortunately, approximately 85% of patients with stage IV CRC have liver disease which is considered unresectable at presentation. However, the rapid expansion in the use of improved combination therapy regimens has increased the percentage of patients eligible for potentially curative surgery. Despite this, the selection criteria for patients potentially suitable for resection are not well documented and patient management by multidisciplinary teams, although essential, is still evolving. The goal of the European Colorectal Metastases Treatment Group is to establish pan-European guidelines for the treatment of patients with CRC liver metastases that can be adopted more widely by established treatment centres and to develop more accurate staging systems and evaluation criteria.

Place, publisher, year, edition, pages
2007. Vol. 43, no 14, 2037-2045 p.
Keyword [en]
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use, Chemotherapy; Adjuvant, Colorectal Neoplasms, Hepatectomy/*methods, Humans, Liver Neoplasms/*drug therapy/secondary/surgery, Preoperative Care/methods
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-13236DOI: 10.1016/j.ejca.2007.07.017ISI: 000250186100011PubMedID: 17766104OAI: oai:DiVA.org:uu-13236DiVA: diva2:41006
Group Author(s): European Colorectal Metastases TreAvailable from: 2008-06-24 Created: 2008-06-24 Last updated: 2011-03-29Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMedhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=17766104&dopt=Citation

Search in DiVA

By author/editor
Arvidsson, DagGlimelius, Bengt
By organisation
Department of Surgical SciencesDepartment of Oncology, Radiology and Clinical Immunology
In the same journal
European Journal of Cancer
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 122 hits
ReferencesLink to record
Permanent link

Direct link