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Medical proton dosimetry using radioluminescence from aluminium oxide crystals attached to optical-fiber cables
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Oncology, Radiology and Clinical Immunology, Avdelningen för sjukhusfysik.
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2007 (English)In: Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, ISSN 0168-9002, E-ISSN 1872-9576, Vol. 580, no 1, 466-468 p.Article in journal (Refereed) Published
Abstract [en]

The prime objective of this study is to investigate if radioluminescence (RL) from carbon-doped aluminum oxide (Al2O3:C) crystals potentially can be used for absorbed dose-rate measurements during proton radiotherapy. The RL from two separate (2 mg) Al2O3:C crystals attached to optical-fiber cables were recorded during irradiations in water in a 175 MeV clinical proton beam. The RL response for low-LET protons in the plateau region of the Bragg curve was found to closely resemble that observed for a clinical 6 MV X-ray beam. An identical response was found in the Bragg peak (where the dose-averaged LET is about 4 keV/mu m) for absorbed doses less than 0.3 Gy. For doses in the range of 0.3-3Gy, we observed a significant decrease in luminescence efficiency with LET. At 3 Gy, the luminescence efficiency was about 60% in the Bragg-peak region. The study implies that the RL-signal from Al2O3:C could potentially be suitable for medical proton dosimetry in the 0-0.3 Gy range even without any LET-dependent correction factors.

Place, publisher, year, edition, pages
2007. Vol. 580, no 1, 466-468 p.
Keyword [en]
radiation-induced luminescence, dosimetry, neutron and proton
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-151549DOI: 10.1016/j.nima.2007.05.129ISI: 000249741300120OAI: oai:DiVA.org:uu-151549DiVA: diva2:410351
Available from: 2011-04-13 Created: 2011-04-13 Last updated: 2017-12-11Bibliographically approved

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Avdelningen för sjukhusfysik
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Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
Medical and Health Sciences

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